Protein Details: Gap junction gamma-3 protein

Protein ID

ICDB_Pro_1368

Protein Name

Gap junction gamma-3 protein

Gene Name

Gjc3; Cx29; Gje1

Organism

Mus musculus (Mouse)

Length

269 amino acids

AlphaFoldDB

AF-Q921C1-F1-model_v4.pdb

Function

Sequence

MLLLELPIKCRMCGRFLRQLLAQESQHSTPVGRFLLPMLMGFRLLILVSSGPGVFGNDENEFICHLGQPGCKTICYDVFRPLSPLRFWAFQVILMAVPSAIYVAFTLYHVIGYWEVPGKENKEQETQISKGDHSKDVSGAKSLKLLWAYVAHLGVRLALEGAALGVQYNLYGFKMSSTFICREDPCIGSTTCFQSHPSEKTIFLNIMFGISGACFLFIFLELALLGLGRFWRIYKHKLSFLKKLPTSESSVRSKDTTDELSVVEAKEPF

PDB Structures

Ligand Binding

1. DICL_CP

2. DICL_Pep

Binding Site

Disease

Location

CNS specific. Expression is restricted to brain; spinal cord; and sciatic nerve.

DOI ID

10.1152/physiolgenomics.00284.2005; 10.1126/science.1112014; 10.1101/gr.2596504; 10.1515/bc.2001.122; 10.1523/jneurosci.22-15-06458.2002; 10.1016/j.cell.2010.12.001

RefSeq

NP_536698.2